cotU [2017-09-06 13:29:37]

spore coat protein

locus: BSU17670

pI: 6.32

mw: 11.42 kDa

protein length: 86 aa

gene length: 258 bp

function: resistance of the spore

product: spore coat protein

essential: no

synonyms: ynzH

Genomic Context

categories

• [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.1|Spore coat proteins] → [category|SW 4.2.1.1.7|Class VI]

Gene

Coordinates: 1,901,117 → 1,901,377

The protein

Paralogous protein(s)

• [protein|9C59B51FC19FC83BD14272008BD441833DD1738E|CotC]

[SW|Localization]

• outer spore coat, localization depends on [protein|825AD8D4315A85CD384F9AF6AD894E38E57C88F7|CotE] [Pubmed|22171814]
• the [protein|9C59B51FC19FC83BD14272008BD441833DD1738E|CotC]-[protein|EB690FA075EAC3E298C47AED082B5FC21E8F8F46|CotU] complex assembles around the forming spore [Pubmed|18065538]

Expression and Regulation

Operons

• genes: [gene|EB690FA075EAC3E298C47AED082B5FC21E8F8F46|cotU]
  description: [Pubmed|22383849]

  sigma factors

  • [protein|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|SigK]: sigma factor, [Pubmed|18065538], in [regulon|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|SigK regulon]

  regulatory mechanism

  • [protein|19228BAD44E6DA3DE908DC390FDF628C18D94E65|GerE]: activation, [Pubmed|18065538], in [regulon|19228BAD44E6DA3DE908DC390FDF628C18D94E65|GerE regulon]
  • [protein|0D7F5504590512E1598B94DC1734BF8FF67ED994|GerR]: repression, [Pubmed|20435725], in [regulon|0D7F5504590512E1598B94DC1734BF8FF67ED994|GerR regulon]

  regulation

  • expressed late during sporulation in the mother cell ([protein|search|SigK], [protein|search|GerE]) [Pubmed|18065538]

Biological materials

Mutant

• MGNA-A021 (ynzH::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/21 NBRP B. subtilis, Japan]

References

Reviews

• 27227299

Original Publications

• 18065538,12562816,20023017,20435725,22171814,26953338